33103

Abstract

Objective: The aim of this study was to identify the correlation of age with hematological parameters in patients admitted in medical oncology department of the Jinnah Postgraduate Medical Centre (JPMC), Karachi, Pakistan.Material and Methods: This was a cross sectional observational study via convenient sampling technique conducted for one and half years from April 2016 to September 2017 in Oncology ward of Jinnah Postgraduate Medical Centre, Karachi after ethical approval. The total of 100 patients who were admitted in haematology oncology unit diagnosed as chronic myeloid leukemia on complete blood count and bone marrow assessment were included in the study. Incomplete data and the patients who did not give informed consent were excluded from the study. SPSS version 20.0 was used. Pearson correlation was applied to assess the relationship and p-value of<0.05 was taken as significant value.Results: A total of 100 patients were included in the study with mean age of 40.29±12.5 years. Mean Hb was 9.65±7.0 g/dl while Hct was 32.85±4.1%. TLC was observed to be 228.7±152.3x103cells/mm3 though platelet count was 466.9±305.09x103cells/mm3. Moreover no correlation existed between age and various hematological parameters in these patients.Conclusion: The present study predicted the median age of40.29 years in patients suffering from chronic myeloid leukemia. Furthermore, no significant difference existed in hematological parameters and therefore no correlation observed with age in various hematological parameters in these patients.Key Words: Chronic Myeloid Leukemia; Correlation;