Acute Kidney Injury in Neonates with Birth Asphyxia: Frequency and Clinical Profile
- Dr seyam waris, Mbbs mc Mirpur
- Maria Shoukat, Ayub Medical College Abbottabad KPK
- Dr Amna Tahir, Saidu medical college swat
- Dr Momina Taqdees Gallani, Azad Jammu and Kashmir medical college muzaffarbad
- Dr Shabnam mujassar, Pouch medical college rawalakot
- Dr Nelofer Shehnaz Tabassum, AJK Medical College Muzafferabad
Abstract
Background: Birth asphyxia is a major neonatal condition leading to multiorgan dysfunction. Acute kidney injury (AKI) is one of the most common complications and significantly increases morbidity and mortality in affected neonates.
Objective: To determine the frequency of acute kidney injury in neonates with birth asphyxia.
Methods: A hospital-based observational study design is commonly used in similar research. Neonates diagnosed with birth asphyxia are evaluated for AKI using serum creatinine, urine output, and neonatal KDIGO criteria within the first 72 hours of life.
Results: The frequency of AKI in neonates with birth asphyxia varies widely across studies, ranging from 20% to over 60% depending on diagnostic criteria, severity of asphyxia, and population studied. Recent studies using standardized neonatal KDIGO definitions report higher and more consistent incidence rates. One study reported AKI in 61.8% of asphyxiated neonates in a tertiary care setting.
Conclusion: Acute kidney injury is a highly frequent complication of birth asphyxia, affecting approximately one-third to two-thirds of affected neonates. Early recognition and monitoring are essential to improve outcomes.
Keywords: injury, neonates, birth Asphyxia. Frequency, acute kidney.